Significant BP minimizing with supplemental dosage out of potassium in the diversity out-of 1900 to 4700 mg/d (49–122 mmol/d) has been stated to effect a result of BP decrease in just as much as 2 so you can 6 mm hg to own diastolic BP and you may 2 to 4 mm hg having systolic BP. the brand new high variability anywhere between efficiency shows the latest variability present in some other knowledge. on top of that, the result from potassium with the BP is actually influenced by pretreatment BP level; age; race; sex; comorbid requirements; intake out-of sodium, magnesium, calcium, or other ions; diet; exercise; weight; sort of potassium made use of; concomitant drugs; and time of fool around with. a listing of the latest results of the many meta-analyses for the outcomes of potassium into BP to date is actually provided from inside the Figure step three.
Breakdown of meta-analyses out-of knowledge investigating the newest hypertension-lowering outcomes of potassium. 25–twenty eight SBP suggests systolic blood pressure level; DBP, diastolic blood pressure level.
Even when contradictory results concerning your outcomes of potassium supplementation towards BP was basically claimed inside the scientific studies, 34, thirty-five new samples keeps showed abilities in line with that of this new meta-research by the Whelton and you will associates twenty-six (Desk II). Gu and coworkers thirty six found that modest potassium supplements (sixty mmol KCl) taken to have twelve weeks lead to a decrease in systolic BP, although not diastolic BP, inside a good Chinese populace. Similarly, Kawano and you can colleagues 37 reported you to good 4-month potassium supplementation period (during which 64 mmol/d of potassium received since slow-release KCl) lead to short however, tall decreases during the workplace, domestic, and you will twenty-four-hour BP from inside the Japanese group. Continue reading « All these meta-analyses manage inform you a dose-reaction matchmaking ranging from BP lowering and you may potassium consumption »